Metatranscriptome analysis of the reef-buidling coral Orbicella faveolata indicates holobiont response to coral disease

White Plague Disease (WPD) is implicated in coral reef decline in the Caribbean and is characterized by microbial community shifts in coral mucus and tissue.Studies thus far have focused on assessing microbial communities or the identification of specific pathogens, yet few have addressed holobiont response across metaorganism compartments in coral

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Note on the PCR threshold standard curve

Abstract Objective The PCR threshold standard curve is based on an exponential model of the initial phase of a PCR run where template replication efficiency is constant cycle to cycle.As such it requires that a threshold is at a level of amplified template not higher than where replication efficiency falls from its initial value.A second requiremen

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A critical role of CDKN3 in Bcr-Abl-mediated tumorigenesis.

CDKN3 (cyclin-dependent kinase inhibitor 3), a dual specificity protein phosphatase, dephosphorylates cyclin-dependent kinases (CDKs) and thus functions as a key negative regulator of cell cycle progression.Deregulation or mutations of CDNK3 have been Maxi Crate implicated in various cancers.However, the role of CDKN3 in Bcr-Abl-mediated chronic my

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